Select Device Freestyle Lingo Freestyle Libre 3 Freestyle Libre 2 Freestyle Libre 14 Day Dexcom G7 Dexcom G6 Dexcom Stelo Guardian Connect Medtronic Simplera Eversense Meter Omnipod Omnipod Dash Medtronic 780G Medtronic 630G Tandem t:slim X2 Bigfoot Unity Medtronic InPen Tempo Pen NovoPen 6/NovoPen Echo Insulin Pen Afrezza CeQur Simplicity Patch V-Go Patch Omnipod GO Patch Syringe and Vial Beta Bionics iLet Pancreas Control IQ with Dexcom Control IQ with Freestyle Libre Medtronic 780G with Smart Guard Omnipod 5 Tandem Mobi Tidepool Loop twiist DIY Loop Apple Series 6/7/8/9/10/SE (2nd Generation) Garmin vívosmart 5™ Garmin Venu Sq 2 Garmin Venu 3 Garmin vivoactive 5 Garmin Fenix 8 Garmin vivofit jr 3 Garmin Forerunner 165/265/965 Garmin epix (Gen 2) Garmin Enduro 3 Fitbit Ace LTE Fitbit Charge 6 Fitbit Inspire 3 Fitbit Versa/Versa 2/4/Versa Lite Fitbit Sense 2 Fitbit Luxe Google Pixel 2/3 Samsung Galaxy 4/5 Xiaomi Mi Band 9 Oura Ring Whoop 4.0 Withings ScanWatch 2 Withings ScanWatch Lite Pedometer 3D Pedometer
Select Device Freestyle Lingo Freestyle Libre 3 Freestyle Libre 2 Freestyle Libre 14 Day Dexcom G7 Dexcom G6 Dexcom Stelo Guardian Connect Medtronic Simplera Eversense Meter Omnipod Omnipod Dash Medtronic 780G Medtronic 630G Tandem t:slim X2 Bigfoot Unity Medtronic InPen Tempo Pen NovoPen 6/NovoPen Echo Insulin Pen Afrezza CeQur Simplicity Patch V-Go Patch Omnipod GO Patch Syringe and Vial Beta Bionics iLet Pancreas Control IQ with Dexcom Control IQ with Freestyle Libre Medtronic 780G with Smart Guard Omnipod 5 Tandem Mobi Tidepool Loop twiist DIY Loop Apple Series 6/7/8/9/10/SE (2nd Generation) Garmin vívosmart 5™ Garmin Venu Sq 2 Garmin Venu 3 Garmin vivoactive 5 Garmin Fenix 8 Garmin vivofit jr 3 Garmin Forerunner 165/265/965 Garmin epix (Gen 2) Garmin Enduro 3 Fitbit Ace LTE Fitbit Charge 6 Fitbit Inspire 3 Fitbit Versa/Versa 2/4/Versa Lite Fitbit Sense 2 Fitbit Luxe Google Pixel 2/3 Samsung Galaxy 4/5 Xiaomi Mi Band 9 Oura Ring Whoop 4.0 Withings ScanWatch 2 Withings ScanWatch Lite Pedometer 3D Pedometer
Summary
The iLet Bionic Pancreas is the first and only commercially-available, automated insulin delivery system that determines 100% of insulin doses without carb counting - offering better results with less work.
The iLet only needs a user's weight to get started. It then learns and adapts to the user's insulin needs based on their meal announcements and CGM data (Dexcom CGM or FreeStyle Libre 3 Plus sensor).
Inhalable regular human insulin. Cartridges come in three doses: 4, 8, and 12-unit doses.
Components
Beta Bionics iLet Pancreas : Pump
Pump connects tubing to a small patch called an infusion set that attaches to the body.
Beta Bionics iLet Pancreas : Sensor
Sensor is inserted underneath the skin, either on the abdomen or arm.
Beta Bionics iLet Pancreas : Controller
Pump receives CGM readings and automatically adjusts insulin delivery. Data from the pump and CGM viewable on compatible smartphones (iOS and Android)
Beta Bionics iLet Pancreas : Infusion Set
An infusion set contains the thin plastic tubing that delivers insulin from the pump to the body.
Afrezza : Inhaler
Small refillable inhaler contains a compartment for powdered insulin containing cartridges.
Afrezza : Cartridge
Cartridges come in three doses: 4, 8, and 12-unit doses. All color coded.
Device Details
Overview
This system requires very little input from the physician or user. It only requires the user to input their weight to get started (glucose targets can be adjusted). Instead of carb counting,* the iLet just needs an estimate of the carbs in your meal – Usual for me, More or Less. The iLet is paired with either a Dexcom CGM or the FreeStyle Libre 3 Plus sensor.
*User must be carb aware.
Nothing on the body when not in use. Visible when dosing.
Affordability and Access
$$$$
iLet and sensors are widely covered and provided by DME and pharmacy. Sensor price range $0-$550/month. iLet cost dependant on your insurance for DME or Pharmacy.
$$$$
Widely covered. Price range; 0-$99/month, depending on insurance coverage. $35/month for medicare and commercial insurance plans.
Data Monitoring Options
Yes
iLet Mobile App provides the ability to pull data from an iLet device to share with the Beta Bionics Cloud.
No Options
Data View Options
Yes
Users can view their iLet data directly on the pump or by using the iLet Mobile App. iLet users can share their data with friends, family, and caregivers through the Bionic Circle App.
No Options
Duration and Storage
3-day pump up to 15 day sensor
Sensors last 10 or 15 days and transmitters last 90 and work at 50ºF – 108ºF. Pump can be used for up to 72 hrs, fully charged iLet will last for 4-5 days, and work between 36°F (2°C) to 86°F (30°C).
10 Days
Open cartridges last up to 10 days. Sealed cartridges may be stored in a refrigerator at 36°F - 46°F until the expiration date.
Vision / Auditory / Dexterity
NO text to speech
YES vibration alerts
A LOT of dexterity needed
NO text to speech
NO vibration alerts
LITTLE dexterity needed
Patient Considerations
Active Lifestyle
No exercise mode. Pump will continue to increase or decrease insulin dosing in response to changing CGM glucose levels as usual. However, insulin can be stopped at user's discretion. Pump is water resistant for up to 12 feet for 30 minutes.
Body free of devices. Does not remain attached to the body.
Avoiding Highs and Lows
Auto basal and bolus insulin. The iLet makes the corrections for you. If you’re trending high, it will automatically give you more insulin to bring you back in range. If you’re trending low, it will reduce your current insulin dosage.
Very short-acting. Absorbs quickly through the lungs to correct high blood sugar but requires attention to prevent lows.
Comfort
Somewhat comfortable. Low maintenance sensor. Larger pump option.
Many components. Have to carry multiple cartridges that can be bulky.
Easy Insulin Dosing
Meal announcement controller. User must be carb aware. The iLet calculates and doses 100% of the insulin throughout the day and night, allowing the user to focus on other things in their lives. Please note: even when you use the "Meal Announcement." your blood glucose levels could rise above 250 mg/dL for a few hours. You'll need to be comfortable letting the iLet regulate your blood glucose.
Less precise but easy dosing. Dosing may be less precise due to the inhaled method of dosing, but color-coded cartridges make dosing easier. Dosing can also be done based on small, medium, or large meals and can be administered 1-2 hours post meals.
Easy to Use
Easiest to Use. User weight is the only input required to start using the insulin pump. No carb counting *, correction factors, carb ratios, or pre-set basal rates required.
*User must be carb aware.
Simple design. Whistle-like device for inhaling insulin.
Fewer Fingersticks
Factory-calibrated sensor. Fingersticks needed for backup only.
Frequent finger-sticks are required.
Privacy
Discreet. Ability to check blood sugar on phone. Minimal pump interaction is required. Pump has tubing but can be clipped to clothing or placed in a pocket to be discreet when needed.
Hideable. Small, discreet, and portable device that's not as noticeable as injections.